Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1986 1
1996 1
1999 1
2001 2
2002 1
2003 1
2005 1
2006 2
2007 2
2008 1
2009 1
2010 2
2012 2
2013 2
2014 3
2015 4
2016 6
2017 5
2018 6
2019 5
2020 4
2021 7
2022 11
2023 5
2024 4

Text availability

Article attribute

Article type

Publication date

Search Results

73 results

Results by year

Filters applied: . Clear all
Page 1
Second Messengers.
Newton AC, Bootman MD, Scott JD. Newton AC, et al. Cold Spring Harb Perspect Biol. 2016 Aug 1;8(8):a005926. doi: 10.1101/cshperspect.a005926. Cold Spring Harb Perspect Biol. 2016. PMID: 27481708 Free PMC article. Review.
Second messengers are small molecules and ions that relay signals received by cell-surface receptors to effector proteins. ...
Second messengers are small molecules and ions that relay signals received by cell-surface receptors to effector proteins. ...
Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations.
Varkaris A, Fece de la Cruz F, Martin EE, Norden BL, Chevalier N, Kehlmann AM, Leshchiner I, Barnes H, Ehnstrom S, Stavridi AM, Yuan X, Kim JS, Ellis H, Papatheodoridi A, Gunaydin H, Danysh BP, Parida L, Sanidas I, Ji Y, Lau K, Wulf GM, Bardia A, Spring LM, Isakoff SJ, Lennerz JK, Del Vecchio K, Pierce L, Pazolli E, Getz G, Corcoran RB, Juric D. Varkaris A, et al. Cancer Discov. 2024 Feb 8;14(2):227-239. doi: 10.1158/2159-8290.CD-23-0704. Cancer Discov. 2024. PMID: 37916958 Free PMC article.
Dopamine and Cognitive Control in Prefrontal Cortex.
Ott T, Nieder A. Ott T, et al. Trends Cogn Sci. 2019 Mar;23(3):213-234. doi: 10.1016/j.tics.2018.12.006. Epub 2019 Jan 31. Trends Cogn Sci. 2019. PMID: 30711326 Review.
This review suggests three major computational roles of dopamine in cognitive control: (i) gating sensory input, (ii) maintaining and manipulating working memory contents, and (iii) relaying motor commands. For each of these roles, we propose a neuronal microcircuit based …
This review suggests three major computational roles of dopamine in cognitive control: (i) gating sensory input, (ii) maintaining and manipu …
A History of Cancer Research: Tyrosine Kinases.
Lipsick J. Lipsick J. Cold Spring Harb Perspect Biol. 2019 Feb 1;11(2):a035592. doi: 10.1101/cshperspect.a035592. Cold Spring Harb Perspect Biol. 2019. PMID: 30709881 Free PMC article. Review.
Proteins containing tyrosine kinase activity play critical roles in cancer signaling. Intracellular SRC-family kinases relay growth signals from numerous cell surface receptors and can be constitutively activated by oncogenic mutations, as can transmembrane growth factor r …
Proteins containing tyrosine kinase activity play critical roles in cancer signaling. Intracellular SRC-family kinases relay growth s …
Ras-Mediated Activation of the Raf Family Kinases.
Terrell EM, Morrison DK. Terrell EM, et al. Cold Spring Harb Perspect Med. 2019 Jan 2;9(1):a033746. doi: 10.1101/cshperspect.a033746. Cold Spring Harb Perspect Med. 2019. PMID: 29358316 Free PMC article. Review.
The extracellular signal-regulated kinase (ERK) cascade comprised of the Raf, MEK, and ERK protein kinases constitutes a key effector cascade used by the Ras GTPases to relay signals regulating cell growth, survival, proliferation, and differentiation. ...
The extracellular signal-regulated kinase (ERK) cascade comprised of the Raf, MEK, and ERK protein kinases constitutes a key effector cascad …
Protein Regulation in Signal Transduction.
Lee MJ, Yaffe MB. Lee MJ, et al. Cold Spring Harb Perspect Biol. 2016 Jun 1;8(6):a005918. doi: 10.1101/cshperspect.a005918. Cold Spring Harb Perspect Biol. 2016. PMID: 27252361 Free PMC article. Review.
Similarly, protein phosphorylation by specific kinases is a key mechanism for augmenting protein activity and relaying signals to other proteins that possess domains that recognize the phosphorylated residues....
Similarly, protein phosphorylation by specific kinases is a key mechanism for augmenting protein activity and relaying signals to oth …
Structure-mechanics statistical learning uncovers mechanical relay in proteins.
Raj N, Click TH, Yang H, Chu JW. Raj N, et al. Chem Sci. 2022 Jan 19;13(13):3688-3696. doi: 10.1039/d1sc06184d. eCollection 2022 Mar 30. Chem Sci. 2022. PMID: 35432911 Free PMC article.
Specifically, by mapping all-atom molecular dynamics simulations onto the spring parameters of a backbone-side-chain elastic network model, the chemical moiety specific force constants (or mechanical rigidity) are used to assemble the rigidity graph, which is the matrix of …
Specifically, by mapping all-atom molecular dynamics simulations onto the spring parameters of a backbone-side-chain elastic network …
Relay Intercropping Winter Cover Crop Effects on Spring Forage Potential of Sweet Maize Stover and Yearling Cattle Beef Performance.
Lauriault LM, Guldan SJ, Popiel-Powers FG, Steiner RL, Martin CA, Falk CL, Petersen MK, May T. Lauriault LM, et al. Animals (Basel). 2022 Jul 28;12(15):1923. doi: 10.3390/ani12151923. Animals (Basel). 2022. PMID: 35953912 Free PMC article.
A 3-year randomized complete block study with three replicates at New Mexico State University's Alcalde Sustainable Agriculture Science Center compared sweet maize (Zea mays var. rugosa) with sweet maize relay intercropped at the V79 stage with cereal rye (rye: Secale cere …
A 3-year randomized complete block study with three replicates at New Mexico State University's Alcalde Sustainable Agriculture Science Cent …
Lipid signaling in T-cell development and function.
Huang YH, Sauer K. Huang YH, et al. Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a002428. doi: 10.1101/cshperspect.a002428. Epub 2010 Oct 13. Cold Spring Harb Perspect Biol. 2010. PMID: 20943760 Free PMC article. Review.
Second messenger molecules relay, amplify, and diversify cell surface receptor signals. Two important examples are phosphorylated D-myo-inositol derivatives, such as phosphoinositide lipids within cellular membranes, and soluble inositol phosphates. ...
Second messenger molecules relay, amplify, and diversify cell surface receptor signals. Two important examples are phosphorylated D-m …
GnRH and the photoperiodic control of seasonal reproduction: Delegating the task to kisspeptin and RFRP-3.
Dardente H, Simonneaux V. Dardente H, et al. J Neuroendocrinol. 2022 May;34(5):e13124. doi: 10.1111/jne.13124. Epub 2022 Apr 5. J Neuroendocrinol. 2022. PMID: 35384117 Review.
Tanycytes respond to TSH through increased expression of thyroid hormone (TH) deiodinase 2 (Dio2), which leads to heightened production of intrahypothalamic triiodothyronine (T3) during longer days of spring and summer. There is strong evidence that this local, long-day dr …
Tanycytes respond to TSH through increased expression of thyroid hormone (TH) deiodinase 2 (Dio2), which leads to heightened production of i …
73 results